Appendix to paper:
Genomic analysis of the TRIM family reveals two groups of genes with
distinct evolutionary properties
M. Sardiello, S. Cairo, B. Fontanella, A. Ballabio and G. Meroni





Human TRIM genes and their orthologs from different vertebrates
Click on the boxes to visualize sequence information of genes (green) and pseudogenes (orange)
TRIM name
Syn
Hs
Mm
Rn
Cf
Bt
Gg
TRIM1 MID2
    
    
    
    
    
     
TRIM2 RNF86, Narf
    
    
    
    
    
     
TRIM3 BERP, HAC1, RNF22, RNF97
    
    
    
    
    
     
TRIM4 RNF87
    


    
    
TRIM5 RNF88
     


    

TRIM6 RNF89
    
    
    
    
    
TRIM7 GNIP, RNF90
    
    
    
    
    
     
TRIM8 GERP, RNF27
     
     
    
    
    
     
TRIM9 RNF91, SPRING
     
     
    
    
    
     
TRIM10 HERF1, RFB30, RNF9
    
    
    
    
    
TRIM name
Syn
Hs
Mm
Rn
Cf
Bt
Gg
TRIM11 BIA1, RNF92
    
    
    
    
    
TRIM13 CAR, LEU5, RNF77, RFP2
     
    
    
    
    
     
KIAA0129* TRIM14, PUB
    
    
    
    
    
     
TRIM15 RNF93, ZNFB7
    
    
    
    
    
EBBP TRIM16
    
    
    
    
    
TRIM17 RBCC, TERF, RNF16
    
    
    
    
    
TRIM18 MID1, FXY, OSX, XPRF, GBB1, RNF59, ZNFXY
    
    
    
    
    
     
TRIM19 PML, MYL, RNF71
    
    
    
    
    
     
PYRIN TRIM20, MARENOSTRIN, FMF, MEFV
    
    
    
    
    
TRIM21 RO/SSA, SSA, RO52, RNF81
    
    
    
    
    
TRIM name
Syn
Hs
Mm
Rn
Cf
Bt Gg
TRIM22 STAF50, RNF94     


    

TRIM23 ARD1, RNF46
    
    
    
    
    
     
TRIM24 PTC6, TF1A, RNF82, TIF1A, hTIF1, TIF1ALPHA
    
    
    
    
    
     
TRIM25 EFP, Z147, RNF147
    
    
    
    
    
     
TRIM26 AFP, RNF95, ZNF173
    
    
    
    
    
TRIM27 RFP, RNF76
    
    
    
    
    
     
TRIM28 KAP1, TF1B, RNF96, TIF1B
    
    
    
    
    
     
ATDC TRIM29
    
    
    
    
    
     
TRIM31 RING, RNF, HCG1, HCGI
    
    
    

    
TRIM32 HT2A, TATIP, LGMD2H
    
    
    
    
    
TRIM name
Syn
Hs
Mm
Rn
Cf
Bt Gg
TRIM33 TIF1q, PTC7, RFG7, TIFG
    
    
    
    
    
     
TRIM34 IFP1, RNF21
    
    
    
    
    
TRIM35 HLS5, MAIR
    
    
    
    
    
     
TRIM36 RNF98, RBCC728, HAPRIN
    
     
    
    
    
     
TRIM37 MUL, TEF3
    
    
    
    
    
     
TRIM38 RNF15
    
    
    
    
    
TRIM39 RNF23
    
    
    
    
    
TRIM40 RNF35
    
    
    

    
TRIM41
    
    
    
    
    
     
TRIM42
    
    
    
    
    
     
TRIM name
Syn
Hs
Mm
Rn
Cf
Bt Gg
TRIM43
    




DIBP TRIM44
    
    
    
    
    
TRIM45 RNF99
    
    
    
    
    
     
TRIM46 TRIFIC
    
    
    
    
    
TRIM47 GOA, RNF100
    
    
    
    
    
RNF101 TRIM48
    




TRIM49 RNF18
    




TRIM50
    
    
    
    
    
     
RNF102 TRIM52
    


    
    
TRIM54 MURF1, RNF30
    
    
    
    
    
TRIM name
Syn
Hs
Mm
Rn
Cf
Bt Gg
TRIM55 RNF29
    
    
    
    
    
     
TRIM56 RNF109
    
    
    
    
    
TRIM58 BIA2
    
    
    
    
    
TRIM59 TRIM57, RNF104, TSBF1
    
    
    
    
    
     
TRIM60 RNF129
    
    
    
    
    
TRIM61
    
    
    
    

TRIM62
    
    
    
    
    
TRIM63 RNF28, MURF2, IRIS
    
    
    
    
    
     
TRIM64
    




TRIM65
    
    
    
    
    
     
TRIM name
Syn
Hs
Mm
Rn
Cf
Bt Gg
TRIM65a
    
    
    
    
    
KIAA0298 TRIM66
    
    
    
    
    
     
TRIM67 TNL
    
    
    
    
    
TRIM68 SS-56, RNF137
    
    
    
    
    
TRIM71 LIN41
    
    
    
    
    
     
TRIM72
    
    
    
    
    
TRIM73
    




TRIM74
    




TRIM75
    
    
    


* The names in green identify the 8 non-canonical TRIM genes



TRIM genes specific to non-primate mammalian orders
Genes paralogous to human TRIM5/6/22/34
Mus musculus Trim12, Trim12a, Trim12b Peptide comparison
Rattus norvegicus Trim12a Peptide comparison
Mus musculus Trim30, Trim30a, Trim30b, Trim30c
Peptide comparison
Rattus norvegicus Trim30b-like1, Trim30b-like2 Peptide comparison
Bos taurus
LOC516599, DQ381150, DQ381151 Peptide comparison
Genes paralogous to human TRIM43/48/49/64
Canis familiaris
Trim64-like1, Trim64-like2, Trim64-like3,
Trim64-like4
Peptide comparison
Bos taurus
Trim64-like1, Trim64-like2, Trim64-like3,
Trim64-like4, Trim64-like5
Peptide comparison
Mus musculus Trim64a Peptide comparison
Rattus norvegicus
Trim64a Peptide comparison
Other human TRIM-related sequences with undefined transcriptional status
TRIM43b, TRIM43ψ1, TRIM48b, TRIM48bBIS, TRIM48ψ1, TRIM48ψ2, TRIM48ψ3, TRIM49b TRIM49cTRIM51b, TRIM51bBIS,TRIM51c, TRIM51ψ1, TRIM51ψ2, TRIM51ψ3, TRIM51ψ4, TRIM64b TRIM64c, TRIM64ψ1, TRIM64ψ2, TRIM64ψ3, TRIM64ψ4, TRIM64ψ5, TRIM64ψ6



Other Gallus gallus TRIM related sequences
Trim39, Trim27.2Trim7.2Trim27, TrimXM414477Trim25likeTrim59like



Tetraodon nigroviridis TRIMs
TnCAG05903, TnCAG09730, TnCAG06722, TnCAG12975, TnCAG11865, TnCAG13222, TnCAG10830, TnCAG96465, TnCAF93916, TnCAG03044, TnCAF92535, TnCAG12384, TnCAG14116, TnCAF95617, TnCAF98545, TnCAF97697, TnCAG02104, TnCAG00228, TnCAF97011, TnCAG01464, TnCAG11221, TnCAG09022, TnCAF97010, TnCAG12264, TnCAF91694, TnCAG01123, TnCAF93116, TnCAG06133, TnCAF94067, TnCAG08216, TnCAF92537, TnCAF96577, TnCAG08725, TnCAF90324, TnCAG04762, TnCAG07558, TnCAF97398, TnCAF97325, TnCAF95730, TnCAG06343, TnCAF91134, TnCAG05781, TnCAF88002, TnCAF99287, TnCAG00441, TnCAF98050, TnCAG06103, TnCAG02380, TnCAG01112, TnCAF90464, TnCAG02574, TnCAG07029, TnCAG12414, TnCAG05274, TnCAF97006, TnCAF96112, TnCAF99480, TnCAF99179.



Ciona intestinalis TRIMs
 CiAK113642, CiAK114964, CiAK113489, CiAK115570, CiAK116296, CiBR000045, CiBr00080, CiBR000123, CiNM001078425, CiNM001078435, CiNM001078455



Danio rerio TRIMs
Zebrafish sequences