TRIM65a
 Multiple alignment of mammalian peptides
Cf = Canis familiaris
Bt = Bos taurus
Mm = Mus musculus Rn =Rattus norvegicus
            1                                                              60
Cf MEKV SWPLQDHNPT
Bt MQRV SRPVQDQAPA
Mm MTSAKLALSS RKGHLDRETM KQRPQRKERR RQSSVHRATK YLALMDMQKI SRSAQDKPPS
Rn MTSAKLGSFL RKGHLDRETM KQQPQRTVRR RRSPVHRAAK YLAVIDMQKI SRPTQDKSPS

61 120
Cf FQPP------ PQAQLLMSNS SVRTFEDQVL CPICLEVFRN PVTTACGHNF CMTCLQGFWD
Bt LQPTAKLSGA PQGQFLMNDS SLCTLEDQVL CPVCLEVFRN PVTTACGHNF CMSCLQGFWD
Mm -QLSSQPSRT PLHLLMGSNS SQHMLEDQVL CPICLEVFCN PVTTACGHNF CMTCLQNFWD
Rn -ELSTQSSRT SLQLLMSSNS SQHLLEDQVL CPICLDVFRN PVTTACGHNF CMTCLQSFWD

121 180
Cf YQATAGETLY CPQCRESFPS RPRLCKNAIL EEMVTCFTQA KDQTLGSSQI LAGPRDVPCD
Bt YQATMGEPLY CPQCRESFPT RPRLCKNVIL EEMVTCFTQA KGQTLGSSRS LAGPRDVPCD
Mm HQAAIGETYY CPQCREAFSS RPRLCKNVIL GEMVACFTQA KSQTSGSLWG LAGPTDVPCD
Rn HQADTGETYY CPQCREAFPS RPRLCKNVIL GEMVACFTLA KSQTSGPLWG LAGPTDVPCD

181 240
Cf FCSPQKLKSV KSCLQCMASL CEKHLRSHFE DQVFQDHQLL EPVWDLKSRL CRKHRKLRRL
Bt FCAPEKLKSV KSCLQCMASL CEKHLRSHLE DQVFHGHQLL EPVWDLKSRL CRKHRKLRRL
Mm FCSPQKLRAA KSCLQCVASL CEKHLRSHFE DQLFQDHQLL DPVWDLTNRL CRKHRKLRQL
Rn FCSPQKLKAT KSCLQCMASL CEKHLHSHFE DPLFQEHQLL DPVWDLKNRL CRKHRKLRQM

241 300
Cf YCRTEGCCVC GACLLEEHKN HDTIPLEEER ARKEVEVRKV QANVENQMLI INSDSQKHRG
Bt YCRTEGCCVC GACLLEEHKN HDTIPLEEER ARKEVEVRKV QANVENQMLI ITSDSQKHRG
Mm YCRTEGSCVC GACLLEEHKN HDTTPLEDER ARKEVEVRKI QANVENQMLI IASDSQKHQG
Rn YCRTEGSCVC GACLLEEHQN HDTTPLEDER ARKEVEVRKI QANVENQMLI IASDSQKHQG

301 360
Cf QVAFLLKLIQ TTRDEVNTCF SEIIQEVKQL QMKVLDFVEK EEAAALGKLG SSIQQSHNRL
Bt QVAFLSKLIQ TTRDEVNACF SEIIQEIKQM QMKVLDFVEK EEAAALGKLG GSIQQSHNRL
Mm RVSFLSKLIQ TMRDEVDTCF SEILHEIKQL QMKVLDFVEK EEAAALGKLG NSIQQSHNRL
Rn RVSFLSKLIQ TMREEVNTCF SEILHEVKQL QMKVLDFVEN EETVALGMLG NSMQQSHSRL

361 420
Cf LKLEGDSIWL RTLLANRSDQ QFLQEFPRLK HFPACMEPLM GTNCEEKQTF LQLPETLAEL
Bt LKLEGDSIWL RSLLANRSDQ QFLQELPRLK HFPACVEPLM GTNCEEKQSF LQLPETLAEL
Mm LKLEGDSVWL HSLLANRSDE QFLQEFPKLK HFPACVEPLL GTNCEETQSF LQLPETLSQL
Rn LKLEGDSVWL HGLLANKSDE QFLQEFPTLK HFPACVEPLL GTNCEETQSF LQLPETLAQL

421 480
Cf RTRLMDVGLS FINQILLKGI KMNSYEVLPP AVDRKILLKC YCNLNFDPTT ASEELFLFKE
Bt RTRLVDMGLS FINQLLLKGI KMNSYEVLPP DVDRKILLKC YCNLNFDATT ASEELFLFKE
Mm RIRLMDIGLS FINQLLLKGI RMSSYEVLPG TVERKTLLQN YCNLNFDPCT ASEELFLFKE
Rn RIRLMDIGLN FINQLLLKGI RMNSYEVLPA TVDRKTLLQN YCNLNFDSSM ASEELFLFKE

481 540
Cf THSVLNLGIL LEPLGAGGPV PGFRQWPQVL CSRGLSEGRH YWEADVSNSW VCLGLTYRRS
Bt THSVLNLGIL LEPFAAGGPF PGFKQWPQVL CSRGLAEGRH YWEADVSNSW VCLGVTYRRS
Mm THSVLNLGIL LEPSTTNSPL PGFKQWPQVL CCPGLSEGCH YWEAEVSNSW MCLGVTYRRS
Rn THSVLNLGIL LEPSTT-SPL PGFKQWPQVL CCPGLSEGCH YWETEVSDSW MCLGVTYRRN

541 600
Cf PPLGGRPRRN TVHLLGRNPY SWCLEWDSLR FSVWHDNAQT VLHGGYHRTL GVALDCGAGC
Bt PPLGGRPRRN IVYLLGRNPY SWCLEWDSLK FSVWHNNTQT VLHGGYHRTL GVLLDCAAGC
Mm PPLSGRPRRN IVYLLGRNPY SWCLEWDSLK FSVWHNNTQT VLHGSYHHTL GVALDFRTGC
Rn PSMSGRHRRN IVYLLGRNPY SWCLEWDSLK FSVWHNNTQT VLHGSYHHTL GVALDFRAGC

601 646
Cf LSFYGVAGGL SLLHRFLGSF LEPLYPAVMV SSGASVTLKQ RPEAEA
Bt LSFYGVAGGV SLLYRFLASF LEPLYPAVMV SSGASVTLKQ RPSEA
Mm LSFYSVAGDV NLLYRFLTSF LEPLYPAVMV SSGASLTLKQ YPEA
Rn LSFYGVAGDV SLLYRFLTSF LEPLYPAVMV SSGASLTLKQ YPEA
 
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