Hs = Homo sapiens
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Cf = Canis familiaris
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Bt = Bos taurus |
Mm = Mus musculus
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Rn =Rattus norvegicus |
1 60 Hs MAKTPSDHLL STLEELVPYD FEKFKFKLQN TSVQKEHSRI PRSQIQRARP VKMATLLVTY Cf MIKTPSDHLL DSLEELLPND FEKFKFKLQN TSVEKDHSRI PRGQVQNAKP VKLANLMINH Bt MVRTRSDHLL YSLEELLPYD FEKFKFKLQN TSLEKEHLRI PRGQLQTAEP VKLASLMVNH Mm MAKTLGDHLL NTLEELLPYD FEKFKFKLQN TSLEKGHSKI PRGHMQMARP VKLASLLITY Rn MANTRVDHLL NTLEELLPYE LEKFKFKLHT TSLEKGHSRI PLSLVKMARP IKLTRLLLTY
61 120 Hs YGEEYAVQLT LQVLRAINQR LLAEELHRAA IQEYSTQENG TDDSAASSSL GENKPRSLKT Cf YGEENAVRLT LQVLRAINQN LLAEELDKAI GPEYLIQESG TYSSAMSCSF GENKSKGLKI Bt YGEEYAVQLT LQVLRAINQH LLAEELHQVI SPECRIQESD TDSSAMSGSS GEMKPKSLKT Mm YGEEYAVRLT LQILRATNQR QLAEELRKAT GTEHLIEENR VGGSVQS--S VENKAKSVKV Rn YGEEYAVRLT LQILRATNQR QLAEELHKAT GPEHLTEENG VGGSVQS--S AENKDKGVKG
121 180 Hs PDHPEGNEGN GPRPYGG--- ----GAASLR CSQPEAGRGL SRKPLSKRRE KASEGL-DAQ Cf SD---GLEGE RQRQSGD--- ----GAVSLP ANQHEAGKGS QKKPQSRRRD QKSSGCPDML Bt PDGLEGDKQR QSADGAGCPP SSQPGAGSPP SSQPEAGRGP QKKPLGKQRD QKGSEGLEVQ Mm PDVPEGDGTQ QNNDESD--- -------TLP SSQAEVGKGP QKKSLTKRKD QRGPESLDSQ Rn SDVPGEDEAQ QNDDESD--- -------ILP PIQAEVGKGP QKKSLAKRKD QRGPESLDSQ
181 240 Hs GKPRTRSPAL PGGRSPGPCR AL-EG---GQ AEVRLRRNAS SAGRLQGL-A G---GAPGQK Cf GKPGARSLSS SSKRSPFPGK LQGEK---GS PTDHLRWNAS SLGLQELS-S GSFTGSLGRV Bt SKLGAKNTTL SSKRSPFLTK VPREKEKGSC PSVRLRRNAS SAGRLQGLTS GSLAGSPGRK Mm TKPWTRSTAP LYRRT-QGTQ SPGDKE--ST ASAQLRRNVS SAGRLQGLYN NA----PGRR Rn TKPGARSAAP LYRRT-LVTQ SPGDKE--NR AGAQLRRNAS SAGRLQGLYS NV----PGRR
241 300 Hs ECRPFEVY-- LPSGKMRPRS LEVTISTGEK APANPEILLT LEEKTAANLD SATEPRARPT Cf KSKIPGER-- LSSGQRRPRS LEFTIFSRER ELLNPETLLS QEKMRSDHTD SAATPSEVAT Bt ETKISEVY-- LPSGKKRPKS LELTISPEET GPLNPEILLL QEKMNTENPS SATTASEVAT Mm ESKKAEVYVY LPSGKKRPRS LEITTYSREG EPPNSEVLPT QE----ETRN GSLIRMRTAT Rn EIKKAEVY-- LPSGKKRPRS LEITTYSKEG EPPNSEALPT QE----ETRN GSLIRTRTAT
301 360 Hs PDGGASADLK EGPGNPEHSV T--------- ---------- ---------- ---------- Cf LD-------- ---------- V--------- ---------- ---------- ---------- Bt LKTGPTVTLE KGFRNPGHAT TLEGTALRNT PLSVPLAGKM MI-------G EHLEPTAPSE Mm LNGRTTGALE KGTGIPEHSM VLDEKTFRNM SSKTSLIGEE RCPTSWTENG NGSPETTESS Rn LNGRTTGTLE KGVGIPEHSM MLDEETSRNM SSKISLTREK RCTASWTENG NGGPETPETL
361 420 Hs ---------- ---------- ---------- ---------- GRPPDTAASP RCHAQEGDPV Cf ---------- ---------- ---------- ---------- GKPQDEAMYP LGHAQEGDPA Bt RSGTGA---- ---------- -PKASSVPHE PSDPEVSPSS GRLQDKAVCP LCRAQEGDPV Mm GETAGSILSD ---PEVPLSL CEKPAKTPED PASLGQAACE GRSQDKAVCP LCHTQEGDLR Rn GETVSSILCD SCSPKVLLSL GEKLAQTPED PASLGQAASK GRSRDKVACP LCHTQ-GELP
421 480 Hs DGTCVRDSCS FPEAVSGHPQ ASGSRSPGCP RCQDSHERKS PGS------- ----LSPQPL Cf DGTYVHDSYR -PAIGSEDLK TSGRYSPSCL SSQASLPIKN SGDVQQKEDL QMAILSPRSL Bt GGSCVHISCS -CSAASRDPE ASLSRSSSCP RCQDLLPGKS HGSHEWQEGL QMASLNPKSL Mm GDTCVQSSCS -CSIAPGDPK AS-GRCSICF QCQGLLARKS ---------- -CEAQSPQSL Rn AKACVQSSCS -CSVAPGDPK AS-GRHSICF QCQSSRAGKS ---------- -CEAQSPQFL
481 540 Hs PQCKRHLKQV QLLFCEDHDE PICLICSLSQ EHQGHRVRPI EEVALEHKKK IQKQLEHLKK Cf PQCERHMKQV QLLFCEDDRE PICLICSLSQ EHRGHRVRPI EEAALEYKVK IQKQLEYVKE Bt PQCKRHMKQA QLLFCEDHGE LICLICRLSQ EHRGHRVRPI EEAALEYKEQ IQKQLDHLKE Mm PQCPRHMKQV LLLFCEDHRE PICLICRLSL EHQGHRVRPI EEAALEYKEQ IREQLERLRE Rn PQCPRHMKQV QLLFCEDHRE PICLICRLSQ EHQGHRVRPI EEAALQYKEQ IRKQLERLRE
541 600 Hs LRKSGEEQRS YGEEKAVSFL KQTEALKQRV QRKLEQVYYF LEQQEHFFVA SLEDVGQMVG Cf LRKSGEEQRS QGDKKTAKFL KQMETQKQRI QHQIEQLYHI LEQQEKFFVA SFEDLNRTIG Bt LRKSGEEQRS QGDKKTVNSL KQAETQKQRI QYQLEQLCQF LEQQERLFVA WLEELGQTIG Mm MRGYVEEHRL QGDKKTDDFL KQTEIQKQKI SCPLEKLYQL LEKQEQLFVT WLQELSQTIS Rn MRGYVEEHKL PADKKAEDFL KQTETQKQRI SCPLEKLFQF LEQQEQLFVT WLQELVQTIG
601 660 Hs QIRKAYDTRV SQDIALLDAL IGELEAKECQ SEWELLQDIG DILHRAKTVP VPEKWTTPQE Cf QVRETYSTQV SRDIALLDEL IGELEAKQFQ PEWELMQDIG VTLHRVKMVT VPKLWNTPLE Bt QVRETYGTQR TRDIALLDKL IGELEAKQCQ PEWELMKDIG VTLHRAKMVT VPELWATPPE Mm KVRETYYTR- ---VSLLDEM IEELEAKQDQ PEWDLMQDIG ITLHRAKMMS ASELLDTPPG Rn KVRETYYTQ- ---VSLLDKL IGELEAKQDQ PEWELMQDIG ATLHRAETMT ASELLGIPPG
661 720 Hs IKQKIQLLHQ KSEFVEKSTK YFSETLRSEM --EMFNVPEL IGAQAHAVNV ILDAETAYPN Cf VEKKIQLFYR KSEFVEKSMK YLSEMLRSEI --DIFNEMLR SEIDIFNANV ILDAETAHPN Bt VKEKIHLLYQ KSEFVEKRVK HFLETLRSEV --ETFNVAEL IGGQAP Mm VKEKLHLLYQ KSKSVEKNMQ CFSEMLSSEM AFSASDVAKW EGRQPSATQV QGLVPTVHLK Rn VKEKLHLLYQ KSKSAEKNMQ RFSEMLGSEM AFSASDVATR EGCRPSTTKA QALIPTVHLK
721 780 Hs LIFSDDLK-S VRLGNKWERL PDGPQRFDSC IIVLGSPSFL SGRRYWEVEV GDKTAWILGA Cf LIFSNNLK-S VRLGNKWNRL PDNPERFDSC IIALGLPSFF SGRHYWEVEV GNKTGWILGI Bt Mm CDGAHTQDCD VVFYPEREAG GSEPKDYLHP QPAQDTPELH ------EIHS RNNKRKFKSF Rn CDGAHTQDFD VILCAELEAG GSEPQDYLHP SSAQDTPELH ------EIHS QNNKRKFKSF
781 840 Hs CKTSISRKGN MTLSPENGYW VVIMMKENEY QASSVPPTRL LIKEPPKRVG IFVDYRVGSI Cf CKASMSRKGS MTLSPDNGYW VVIMMKRSEY QVSTIPPTRL QLREPPKRVG IFLDYKAGDI Bt Mm LKWKPSFSRT DWRLRTCCYR DLDQAAAHPN LIFSMI Rn LKWKPSFSRT DRCLRTCW
841 892 Hs SFYNVTARSH IYTFASCSFS GPLQPIFSPG TRDGGKNTAP LTICPVGGQG PD Cf SFYNVTNKSL IYAFTGFSSS EPLQPIFSPG THDGGKNMDP LTICPVGDQE PH Bt Mm Rn
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