Hs = Homo sapiens
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Cf = Canis familiaris
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Bt = Bos taurus |
Mm = Mus musculus
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Rn =Rattus norvegicus |
1 60 Hs M EPAPARSPRP QQDPARPQEP TMPPPETPSE GRQPSPSPSP TERAPASEEE Cf MQQ EPAPPRSPAP GQDPAPSGAP SMPPPEPASE GHQPSPSRSP AEQA--LEEE Bt MQQ DPEPAGSPGP QQDPALPHSP SMPPPESLSE GHQSSHSDSP TEQA--TEEE Mm METEPVSEQK VPAPPGSPCR QQDSALTPTP TMPPPEEPSE DYE--HSQSR AEQA--IQEE Rn MPPPEEPSE DHE--HSQSP AEQA--IKEE
61 120 Hs FQFLRCQQCQ AEAKCPKLLP CLHTLCSGCL EASGMQCPIC QAPWPLGADT PALDNVFFES Cf FQFLCCQSCQ AEAKCPKLLP CLHTLCSGCL EASGLRCSIC QVPGPLGAGS PALDNVFFES Bt FQFLRCQGCR AEAKCPKLLP CLHTLCSGCL EESSMQCPVC RAPWPSGAGT QALDNVFFES Mm FQFLRCPSCQ AQAKCPKLLP CLHTLCSGCL EAPGLQCPIC KAPGQADANG EALDNVFFES Rn FQFLRCPGCQ TQAKCPKLLP CLHTLCSGCL EAPGLQCPIC QAPGSANANA EALDNVFFES
121 180 Hs LQRRLSVYRQ IVDAQAVCTR CKESADFWCF ECEQLLCAKC FEAHQWFLKH EARPLAELRN Cf LQRRLSVYRQ IVDAQAVCTR CKEPADFWCF ECEQLLCAKC FEAHQWFLKH EARPLAELRS Bt LQRRLSVYQQ IAREQAFCTR CKEPAHYWCF ECEQLICTKC FEAHQWFLKH EARPLAELRS Mm LQRRLAVFRQ IVDAQAACTR CKGLADFWCF ECEQLICSKC FEAHQWYLKH EARPLADLRD Rn LQRRLAVFRQ IVDAQAACTR CKELADFWCF ECEQLMCGKC FDAHQWYLKH EARPLAELRD
181 240 Hs QSVREFLDGT RKTNNIFCSN PNHRTPTLTS IYCRGCSKPL CCSCALLDSS HSELKCDISA Cf QSVCEFLDST RKSNSIFCSN PNHRTPMLTS IYCRGCSKPL CCSCALLDSS HGELKCDISA Bt QSVREFLDGT RKSNIIFCSN PNHRSPMLTS IYCRGCSKPL CCSCALLDRG HSELKCDISM Mm NSVSSFLDST RKSN-IFCSN TNHRNPALTD IYCRGCAKPL CCTCALLDRN HSHLHCDIGE Rn NSVREFLDST RKSN-IFCSN TNHRTPAQTN IYCRGCAKPL CCECALLDRN HSHLQCEIGK
241 300 Hs EIQQRQEELD AMTQALQEQD SAFGAVHAQM HAAVGQLGRA RAETEELIRE RVRQVVAHVR Cf EIQQRQEELD TMARVLQEQD GAFGAAHAQM HSAVSQLGRA RADTEALIHA RVRQLVEHVL Bt EIQQRQDELD TMTQDLQEQD RTFGAAQAQM RSAISQLGRV RADTEEFIRE RVREVVAHVL Mm EIQQWHEELG TMTQTLEEQG RTFDSAHAQM CSAIGQLDHA RADIEKQIRA RVRQVVDYVQ Rn EIQQLHEELG TMTQALEEQG RTFDSAHAQM HSAIGQLDDA RSDTEKQIRA RVRQVIEHVQ
301 360 Hs AQERELLEAV DARYQRDYEE MASRLGRLDA VLQRIRTGSA LVQRMKCYAS DQEVLDMHGF Cf AREQELLAGV TARYQRCYEE LAGRMGRLEA VLQRIRTGSA LVRRMKLYAS DQEVLDMHGF Bt EQERELLQGV GARYQRDYEE IAGQLGRLDA VLQRIRMGSV LVQRMKLYAS DQEVLDMHDF Mm AQERELLEAV NDRYQRDYQE IAGQLSCLEA VLQRIRTSGA LVKRMKLYAS DQEVLDMHSF Rn AQERELLEAV NVRYQRDYQE IAGQLGHLEA VLQRIRTGGA LVKRMKLYAS EQEVLDMHGF
361 420 Hs LRQALCRLRQ EEPQSLQAAV RTDGFDEFKV RLQDLSSCIT QGKDAAVS-- ---------- Cf LRDALHRLRQ EEPHDLHTAV RTDGFEEFKV RLQELVSCIT RGTDLAVP-- ---------- Bt LRKALHQLRQ EEPQSLRATV HTDSFDEFRV RLQDLVSCIT RGTDAALS-- ---------- Mm LRKALCSLRQ EEPQNQKVQL LTRGFEEFKL CLQDFISCIT QRINAAVAS- ---------- Rn LRKALCRLRQ EEPQNHKVQL RTSGFEEFKL CLQDLVSFIT QRTDVAVAGR ASPEAASTHP
421 480 Hs ---------- ------KKAS PEAASTPRDP IDV----D-L PEEAERVKAQ VQALGLAEAQ Cf ---------- ------RRAS PDAAGTPRDS LDV----DQT PPPEEMLESP AQAPQLTETH Bt ---------- ------RRAS PEAASTPRDT CGT----D-- -PPEEVPRDQ MQASGL---- Mm ---------- ---PEAASNQ PEAASTHPVT TSTP---EDL EQPKEVQSVQ AQALELSKTQ Rn EAASAQPEAA STHPEAASAQ PEAASAHPES ASTPGNSTDL EQPKEVQRAQ AQAMELSKTQ
481 540 Hs PMAVVQSVPG AHPVPVYAFS IKGPSYGEDV SNTTTAQKRK CSQTQCPRKV IKMESEEGKE Cf TGALVQSVPG VHPVPVHAYS IRDPSCREEV CNKVTPQKRK SCQTECPRKA IKMESEEERE Bt --AVVQPVPG AHPVPVYAFS IQDPSLREEG TNTTTPQKRK ACQTECPRKA VKMESEEGEE Mm PVAMVKTVPG AHPVPVYAFS MQGPTYREEA SQTVGSMKRK CSHEDCSRKI IKMESTEENE Rn PVAMVKSVPG AHPVPVYAFS MQGPTYREEA SQTVSPMKRK CCHIDCCRKI IKMESTDENE
541 600 Hs ARLARSSPEQ PRPSTSKAVS PPHLDGPPSP RSPVIGSEVF LPNSNHVASG AGEAEERVVV Cf TRLAQSSPEQ PRPSTSKAVS PP-LDGPSSP ESPIMGNEVF LPNSNHSTGD PGEAEERVVV Bt SRLAWSSPEQ PRPSTSRAVS PPHLDGPPSP KSPIVRDELS LPESNHQTGD PAETEERVVV Mm DRLATSSPEQ SWPSTFKATS PPHLDGTSNP ESTVPEKKIL LPNNNHVTSD TGETEERVVV Rn DRLSTSSPEQ PRPSTSKAIS PPHPDGTSST ESTIPEKETP LPNNNHVASD AGETEERIVV
601 660 Hs ISSSEDSDAE NSSSRELDDS SSESSDLQLE GPSTLRVLDE NLADPQAEDR PLVFFDLKID Cf ISSSEDSDAE NSSSRELDDS SSESSDLQLE GPSSLRVLDN SLADPQAEDR PLVFFDLKID Bt ISSSEDSDAE NPDSRELADN SSESSDLQLE GPSSLGVLDD SPSNSLVEDK PLVFFDLKID Mm ISSSEDSDTE NLSSHELDDS SSESSSLQLE GPNSLKALDE SLAEPHLEDR TLVFFDLKID Rn ISSSEDSDAE NLPSHELDDS SSESSSIQLE GPNSLKALDE SLAEPHLEDR TLVFFDLKID
661 720 Hs NETQKISQLA AVNRESKFRV VIQPEALFSI YSKAVSLEVG LQHFLSFLSS MRRPILACYK Cf SETQKISQLA AVNRESEFRV LIQPQAYSSM FSKAVSLEVG LQHFLGFLGS MRRPVLACSK Bt NETQKISQLA AVNQESQFRA LIQPEVL-NV YSKAVSLEVG LQHFLHFLAS MRQPILACYK Mm NETQKISQLA AVNRESKFRV LIQPEAF-SV YSKAVSLEAG LRHFLSFLTT MHRPILACSR Rn NETQKISQLA AVNRESKFRV LIQPEAF-SV YSKAVSLESG LQHFLSFLNS MHRPLLACPR
721 780 Hs LWGPGLPNFF RALEDINRLW EFQEAISGFL AALPLIRERV PGASSFKLKN LAQTYLARNM Cf LWGPSLPIFF RALEDMNRLW GFQEAISGFL AVLPLVRERV PQASSFRLRS LAKTYLARNV Bt LWGPSLPSFF QALEEMNMLG KFQKSISGFL ATLPLIRECV PGASSFKLKS LAKTYLARNM Mm LWGPGLPIFF QTLSDINKLW EFQDTISGFL AVLPLIRERI PGASSFKLGN LAKTYLARNM Rn LWGPGLPIFF QALNDINKLW EFQDAISGFL AVLPLIQERI PSASSFKLRN LAKTYLARNM
781 840 Hs SERSAMAAVL AMRDLCRLLE VSPGPQLAQH VYPFSSLQCF ASLQPLVQAA VLPRAEARLL Cf NERSALATVL ALRDLCRLLE ISPGPWLAQH VYSFSSLQCF ASLQPLVQAA ALAQAQARLL Bt SERSALAAVL TMRDLCRLLE VSPSPQLALH VHPFSSLQCF SSLQPLVRAA ILPRAEARLL Mm SERSALASVL AMRDLCCLLE ISPGLPLAQH IYSFSSLQCF ASLQPLIQAS VLPQSEARLL Rn SERSALAAVL AMRDLCCLLE VSPGLQLAQH IYSFSSLQCF ASLQPLIQAQ VLPQPEARLL
841 900 Hs ALHNVSFMEL LSAHRRDRQG GLKKYSRYLS LQTT---TLP PAQPAFNLQA LGTYFEGLLE Cf ALHNVSFTEL LAAHRRDPQQ GLKKYSRYLG PQTS---TSP PSQRAVSLQA LSTYFKGRSE Bt ALHKVTFIEL LTAHHHDPQG GLKKYNRFLS LQSP---TS- -SQPVFDLHS LGTYFEGLLG Mm ALHNVSFVEL LNAYRTNRQE GLKKYVHYLS LQTTPLSSSA STQVAQFLQA LSTHMEGLLE Rn ALHNVSFLEL LTAYRSNRQE GLKKYVHYLS LQTTP--SSA STQIAQFLQA LSAYMDGQLE
901 927 Hs GPALARAEGV STPLAGRGLA ERASQQS Cf GAVSAPAQGL STLLTGHSFA KRACQQS Bt APASAGAGGV AAPPAGHSLA ERATQQT Mm GHAPAGAEG- ------KAES KGCLA Rn GHIPAGAEGT ALSLSGRAEN KGCLA
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